Gas Exchange in the Alveoli

Laura Armstrong & Joe Wolfensohn

Teachers

Laura Armstrong Joe Wolfensohn

Recall Questions

This topic requires prior knowledge of diffusion to understand how oxygen and carbon dioxide are exchanged efficiently.

How does increasing surface area affect the rate of diffusion?

It Increases the rate of diffusion

State an example of a substance that diffuses into cells.

Oxygen / Glucose / Amino acids

Why are exchange surfaces 1 cell thick?

To reduce the diffusion distance, to increase the rate of diffusion

Topic Explainer Video

Check out this @JoeDoesBiology video that explains gas exchange in the alveoli, then read the study notes. Once you’ve gone through them, don’t forget to try the practice questions!

Gas Exchange in the Alveoli

What are Alveoli?

  • Alveoli are tiny (0.2mm) air sacs in the lungs.
  • They are the site of gas exchange between the air and the blood.
  • Found at the ends of bronchioles in clusters.
  • There are millions of alveoli in the lungs.

Gases Involved in Exchange

  • Oxygen diffuses from the alveoli into the blood.
  • Carbon dioxide diffuses from the blood into the alveoli to be exhaled.

Diagram of the human respiratory system showing the trachea, bronchi, lungs, diaphragm and an inset of bronchioles leading to alveoli for gas exchange.

Adaptations of the Alveoli (to maximise diffusion)

Adaptation

Explanation

Large surface area

Millions of alveoli provide a huge surface area for diffusion.

Thin walls

Walls are one cell thick, reducing the diffusion distance.

Good blood supply

Maintains a steep concentration gradient for oxygen and carbon dioxide with constant blood flow. For example, blood moving into the capillary will be deoxygenated, so there will always be a higher concentration of oxygen in the air in the alveolus than in the blood.

Continuous ventilation

Breathing in fresh air means there will always be air with a higher concentration of oxygen in the alveoli than in the blood, maintaining a steep concentration gradient for oxygen. 

Diagram of an alveolus surrounded by capillaries, showing oxygen diffusing into the blood and carbon dioxide diffusing into the alveolar air for exhalation.

Key Terms

  • Alveolus (plural: alveoli) – tiny air sac in the lungs.
  • Diffusion – net movement of particles from a higher to a lower concentration.
  • Capillary – small blood vessels surrounding alveoli.
  • Ventilation – movement of air in and out of the lungs.
No answer provided.

Exam Tips

  • Link the factors that affect the rate of diffusion to the adaptations of the alveoli.
  • Do not say the alveoli are thin, it is the walls of the alveoli which are thin!
No answer provided.

Practice Question

Explain how the alveoli are adapted to maximise gas exchange. (3 marks)

  • Alveoli have a large surface area to increase diffusion.
  • The walls are 1 cell thick, reducing the diffusion distance.
  • A rich blood supply maintains a steep concentration gradient for oxygen / carbon dioxide.

More Practice

Try to answer these practice questions from the TikTok videos on your own, then watch the videos to see how well you did!